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| 中期和晚期乳腺单纯癌癌细胞形态参数的逐步判别分析 | |
| 引用本文： | 刘美玉,陈平,李维波,钱纬,刘爱武,魏万里. 中期和晚期乳腺单纯癌癌细胞形态参数的逐步判别分析[J]. 中国体视学与图像分析, 2001, 6(1): 26-28 |
| 作者姓名： | 刘美玉 陈平 李维波 钱纬 刘爱武 魏万里 |
| 作者单位： | 1. 昆明医学院物理教研室,云南昆明,650031 2. 昆明医学院电镜室,云南昆明,650031 3. 昆明医学院第三附属医院,云南昆明,650031 |
| 基金项目： | 云南省教委应用基础研究基金资助课题(9512002) |
| 摘 要： | 用体视学方法分别对20例中期和20例晚期乳腺单纯癌癌细胞、细胞核、核仁的17个形态参数进行了测定和分析,并用逐步判别分析法筛选出3个最佳参数,建立了判别函数.研究发现,与正常细胞比较,癌细胞比表面明显减小,晚期癌最小(即细胞体积最大),同时癌细胞核体积和周长明显增大,晚期癌最大,这表明癌细胞及癌细胞核的体积越大,癌细胞核周长越长,癌细胞恶化程度越高. |
| 关 键 词： | 体视学 细胞 细胞核 乳腺单纯癌 逐步判别分析 |
| 文章编号： | 1007-1482(2001)01-0026-03 |
| 修稿时间： | 2001-01-03 |
STEPWISE STATISTICS ANALYSIS OF MORPHOLOGICAL PARAMETERS IN MID STAGE AND LATE STAGE OF SIMPLE CARCINOMA OF BREAST |
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| LIU Mei-yu ,CHEN Ping ,LI Wei-bo ,QIAN Wei ,LIU Ai-wu ,WEI Wan-li. STEPWISE STATISTICS ANALYSIS OF MORPHOLOGICAL PARAMETERS IN MID STAGE AND LATE STAGE OF SIMPLE CARCINOMA OF BREAST[J]. Chinese Journal of Stereology and Image Analysis, 2001, 6(1): 26-28 | |
| Authors: | LIU Mei-yu CHEN Ping LI Wei-bo QIAN Wei LIU Ai-wu WEI Wan-li |
| Affiliation: | LIU Mei-yu 1,CHEN Ping 1,LI Wei-bo 1,QIAN Wei 2,LIU Ai-wu 2,WEI Wan-li 3 |
| Abstract: | Stereologic method was applied to analyse 17 morphological parameters of breast carcinoma cells, nuclei and nucleolus in 20 cases with breast carcinoma simplex. At last, the best three parameters were obtained and distinguish function was set up with mathematics statistical stepwise method. The result showed that compared with normal cell the specific surface of the cancer cells were obviously decreased, the specific surface was least in the late stage in breast carcinoma (the volume of the cancer cells were most). Synchronously the volume and perimeter were obviously increased in breast carcinoma and were most in the late stage in breast carcinoma. All these results mentioned above the greater the volume and the perimeter of cells and nucleus in breast carcinoma, the higher the degree of the cancer cells depravation. |
| Keywords: | stereology cell nucleus simplex breast carcinoma stepwise statistics |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |