原发性鼻腔癌128例的治疗分析

目的 探讨鼻腔癌的最佳治疗手段和影响预后的因素。方法 对本院自１９７７年３月～１９９３年８月收治的１２８例鼻腔癌进行回顾性分析。治疗方式：单纯放射治疗８９例，术前放射治疗＋手术２１例，手术＋术后放射治疗１３例，单纯手术５例。结果 １２８例鼻腔癌患者的总５年生存为４２．２％；单纯放射治疗５年生存率为３３．７％；术前放射治疗＋手术的５年生存率５７．１％（Ｐ〈０．０５）；手术＋术后放射治疗的５年生存率为

Treatment of cancer of the nasal cavity in 128 cases]

OBJECTIVE: To investigate the credibility of combined radiotherapy and surgery for cancer of the nasal cavity and their prognostic factors. METHODS: One hundred and twenty-eight patients were treated from Mar. 1977 to Aug. 1993 receiving either radiotherapy alone (R group, 89), radiotherapy plus surgery (R + S group, 21), surgery plus radiotherapy (S + R group, 13), or surgery alone (S group, 5). RESULTS: The overall 5-year survival rate was 42.2%. The 5-year survival rates of R, R + S and S + R groups were 33.7%, 57.1% and 61.5%, respectively. The 5-year survival rate of combined therapy for squamous cell carcinoma and low differentiated cancer were higher than that of radiotherapy alone, and the effect of radiotherapy alone for undifferentiated carcinoma was better. In early stage, the 5-year survival rate of the radiotherapy alone and combined therapy did not differ significantly. For III and IV stages, the 5-year survival rate of R + S combined therapy was higher than those with radiotherapy alone (P < 0.01). CONCLUSIONS: For early lesions(Stage I and II), R alone or R + S give better results. For advanced lesions(Stage III and IV), combined radiotherapy and surgery is preferred. Radiotherapy alone is indicated for poorly differentiated cancers. Combined radiotherapy plus surgery is preferred for squamous cell carcinoma.