风湿性疾病患者血清弓形虫抗体检测分析

目的：了解风湿性疾病患者弓形虫感染的情况。方法：采用ELISA法对346例风湿性疾病患者进行血清弓形虫IgG、IgM检测。结果：在被检患者中,IgG阳性率21.68%,其中男性阳性率17.00%,女性阳性率16.34%,两者比较无统计学意义（P〉0.05）;IgM阳性率20.52%,其中男性阳性率17.62%,女性阳性率17.10%,两者比较无统计学意义（P〉0.05）。类风湿性关节炎（RA）、系统性红斑狼疮（SLE）、风湿热（RF）患者IgG阳性率分别为23.83%、20.46%、20.59%,明显高于多发性肌炎（PM）、皮肌炎（DM）、干燥综合征（SS）患者的12.50%、10.00%、15.38%（P〈0.05）。RA,SLE,RF患者IgM阳性率分别为21.24%、21.59%、23.53%,明显高于PM,DM,SS患者的12.50%、10.00%、7.69%（P〈0.05）。结论：风湿性疾病患者弓形虫感染率较高,尤其是RA,SLE,RF患者。

Detection Analysis of Toxoplasma Gondii Antibody in Rheumatic Patients

Objective: To explore the relation between rheumatic patients and the infection of Toxoplasma gondii.Methods: ELISA was applied to detect TOX-IgG、IgM in 346 rheumatic patients.Results: The positive rate of IgG was 21.68%;the male and female were 17.00% and 16.34%,respectively.The positive rate of IgM was 20.52%;the male and female were 17.62% and 17.10%,respectively.The result showed that there were no significant statistically differences between different gender(P>0.05).The positive rates of IgG in patients with RA,SLE and RF(23.83%,20.46%,and 20.59% respectively) were higher than those of patients with PM,DMand SS(12.50%,10.00%,15.38%,respectively P<0.05);the positive rate of IgM in patients of RA,SLE and RF(21.24%,21.59%,23.53%,respectively)were higher than that of the patients with PM,DM and SS(12.50%,10.00%,7.69%,respectively,P<0.05).Conclusion: The infection rate of toxoplasma gondii in rheumatic patients is higher than normal people,especially in RA,SLE and RF patients.