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| CD20 CD45RA和溶菌酶在颜面粟粒性狼疮中的检测 | |
| 引用本文： | 郑凤兰,雷明君,赵宝亭,高顺强,林元珠. CD20 CD45RA和溶菌酶在颜面粟粒性狼疮中的检测[J]. 中国皮肤性病学杂志, 2005, 19(4): 203-205 |
| 作者姓名： | 郑凤兰 雷明君 赵宝亭 高顺强 林元珠 |
| 作者单位： | 1. 河北医科大学第四医院皮肤科,河北,石家庄,050011 2. 河北医科大学中医院皮肤科,河北,石家庄,050017 |
| 摘 要： | 目的进一步探讨颜面粟粒性狼疮(LMF)的发病机理。方法采用免疫组化SP法对32例LMF患者皮损中CD20,CD45RA和溶菌酶进行检测。结果CD20,CD45RA和溶菌酶在颜面粟粒性狼疮中的表达明显高于正常对照组。结论在本病的发生发展中,T细胞介导的细胞免疫占有主导地位;B细胞可能仅作为抗原递呈细胞参与了本病的发病过程;溶菌酶亦起着主要作用。 |
| 关 键 词： | 颜面粟粒性狼疮 CD20 CD45RA 溶菌酶 免疫组化 |
| 文章编号： | 1001-7089(2005)04-0203-03 |
Detection of CD20, CD45RA and LZM In Lupus Miliaris Faciei |
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| ZHENG Feng-lan,LEI Ming-jun,ZHAO Bao-ting,et al. Detection of CD20, CD45RA and LZM In Lupus Miliaris Faciei[J]. The Chinese Journal of Dermatovenereology, 2005, 19(4): 203-205 | |
| Authors: | ZHENG Feng-lan LEI Ming-jun ZHAO Bao-ting et al |
| Abstract: | Objective To research the pathogenesis of lupus miliaris faciei further. Methods The detection of CD20,CD45RA and LZM in 32 patients’ lesions were studied by histostain-SP method in immunohistochemistry.Results The detection of CD20,CD45RA and LZM in LMF were higher than that of normal tissues of faciei.Conclusion In the occurrence and development of this disease,T cell mediated cytoimmunity play a main role;B cell may participate in the pathogenetic progresss merely as antigen submission cells;LZM is also an important factor. |
| Keywords: | Lupus miliaris faciei CD20 CD45RA LZM Immunohisto-chemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |