鼻内镜治疗慢性鼻-鼻窦炎疗效及影响因素分析

目的探讨慢性鼻-鼻窦炎术后疗效及影响疗效的相关因素。方法回顾性分析200例经鼻内镜手术的慢性鼻一鼻窦炎患者的临床资料，通过t检验了解术后疗效，Logistic回归模型分析影响慢性鼻-鼻窦炎患者手术预后的诸因素。结果患者术后症状明显改善，相关因素分析表明慢性鼻-鼻窦炎患者是否伴有鼻息肉、是否长期应用鼻减充血剂、是否有前期鼻窦手术史、是否伴变应性鼻炎病史、是否坚持鼻内镜术后的综合治疗是影响慢性鼻-鼻窦炎手术预后的相关因素。结论功能性鼻内镜手术作为治疗慢性鼻-鼻窦炎、鼻息肉最有效的临床方法之一，能够明显地改善患者的症状，同时强调鼻内镜术后的综合治疗，包括术后随访和鼻腔清理，鼻内糖皮质激素、黏液稀化剂和抗生素的联合应用。

Therapeutic effect and its related factors in endoscopic surgery for chronic rhinosinusitis

Objective To investigate the therapeutic effect and its related factors in endoscopic surgery for chronic rhinosinusitis （ CRS ）. Methods Clinical data of 200 CRS patients treated with endoscopic surgery was analyzed retrospectively. The surgical effect was evaluated by t-test and its related factors were analyzed by logistic regression model analysis. Results Symptoms of CRS got improved significantly in all patients. Logistic regression model analysis showed that coexistence of nasal polyp and allergic rhinitis, long-term use of nasal decongestant, previous sinus surgical history, and comprehensive treatment after endoscopic surgery were independent prognostic factors. Conclusions Functional endoscopic sinus surgery is the most effective treatment strategy for CRS. To improve the therapeutic effect, postoperative comprehensive treatment, including follow-up management, nasal clearance, combined application of intranasal corticosteroids, mucus thinning agents and antibiotics, should be emphasized.