| 白细胞介素-10在莱姆病中的作用及其机制的研究进展 |
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| 引用本文： | 李劲涛,;冯时,;李冰雪,;宝福凯. 白细胞介素-10在莱姆病中的作用及其机制的研究进展[J]. 中国病原生物学杂志, 2014, 0(8): 753-756 |
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| 作者姓名： | 李劲涛, 冯时, 李冰雪, 宝福凯 |
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| 作者单位： | [1]昆明医科大学神经科学研究所,云南昆明650500; [2]云南省高校热带传染病重点实验室;,云南昆明650500; [3]云南省公共卫生与疾病防控协同创新中心;,云南昆明650500; [4]昆明医科大学热带医学研究所;,云南昆明650500; [5]昆明医科大学病原生物学与免疫学系,云南昆明650500; |
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| 基金项目： | 国家自然科学基金项目（No.81060134;81371835）;云南省自然科学基金项目（No.2010CD221,2011FB244,2012FB011,2013FZ057） |
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| 摘 要： | 近年来,白细胞介素10(IL-10)与莱姆病的关系及其相关机制是目前研究的热点问题。如何利用IL-10的抗炎作用及对炎症的调控而对莱姆病采取积极有效的预防、治疗措施是近来研究的焦点。本文概述了白介素-10在莱姆病中的作用及其机制方面的研究进展。
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| 关 键 词： | 莱姆病 白细胞介素10 机制 综述 |
The effect of IL-10 on Lyme disease and its mechanism of action |
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| LI Jing-tao;SHI Feng;LI Bing-xue;BAO Fu-kai. The effect of IL-10 on Lyme disease and its mechanism of action[J]. Journal of Pathogen Biology, 2014, 0(8): 753-756 |
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| Authors: | LI Jing-tao SHI Feng LI Bing-xue BAO Fu-kai |
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| Affiliation: | LI Jing-taou , SHI Feng2＇3＇4 , LI Bing-xue2＇3＇4＇5 , BAO Fu-kai2＇3＇4＇5 (1. The Institute of Neuroscience, Kunming Medical University, Kunming 650500, China 2. Yunnan Key Laboratory for Tropical Infectious Diseases ; 3. Yunnan Collaborative Innovation Center for Public Health and Disease Control ; 4. The Institute for Tropical Medi- cine, Kunming Medical University 5. DepartmeNt of Microbiology and Immunology, Kunming Medical University) |
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| Abstract: | Current studies are interested in the role of IL-10,a type of anti-inflammatory cytokine,in Lyme disease and its mechanism of action.Recent studies have focused on possible use of the anti-inflammatory action of and modulation of inflammation by IL-10 to actively and effectively prevent and treat Lyme disease.IL-10 and Lyme disease are reported to be related.To the extent known,however,few systematic studies have reported on the effect of IL-10 on Lyme disease,let alone on the detailed mechanism responsible.This paper reviews the effect of IL-10 on Lyme disease and its mechanism of action in order to provide new insight into the pathogenesis of Lyme disease and its treatment via an IL-10 intervention. |
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| Keywords: | Lyme disease interleukin-10 mechanism review |
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