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Characteristics of high-density lipoprotein binding sites in cultured parenchymal,endothelial, and Kupffer's cells from rat liver
Authors:E. V. Zaitseva  W. Huang  T. G. Vishnyakova  E. G. Frolova  V. S. Repin  A. V. Bocharov
Affiliation:(1) Institute of Experimental Cardiology, Cardiological Research Center, Moscow;(2) Russian Academy of Medical Sciences, Moscow
Abstract:
Liver endothelial cells posses surface high-affinity binding sites for HDL3, whose affinity is 4 times higher than that of the sites on hepatocytes and Kupffer's cells. The maximal number of high-affinity binding sites on endothelial cells is 437 ng/mg protein, which surpasses this parameter on the hepatocyte surface several times. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N o 3, pp. 268–270, March, 1994
Keywords:high-density lipoproteins  hepatocyte culture  liver endothelium culture  Kupffer's cell culture  Scatchard analysis
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