Characteristics of high-density lipoprotein binding sites in cultured parenchymal,endothelial, and Kupffer's cells from rat liver |
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Authors: | E. V. Zaitseva W. Huang T. G. Vishnyakova E. G. Frolova V. S. Repin A. V. Bocharov |
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Affiliation: | (1) Institute of Experimental Cardiology, Cardiological Research Center, Moscow;(2) Russian Academy of Medical Sciences, Moscow |
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Abstract: | Liver endothelial cells posses surface high-affinity binding sites for HDL3, whose affinity is 4 times higher than that of the sites on hepatocytes and Kupffer's cells. The maximal number of high-affinity binding sites on endothelial cells is 437 ng/mg protein, which surpasses this parameter on the hepatocyte surface several times. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N o 3, pp. 268–270, March, 1994 |
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Keywords: | high-density lipoproteins hepatocyte culture liver endothelium culture Kupffer's cell culture Scatchard analysis |
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