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A case report-the marked response to S-1 + CDDP chemotherapy for post-operative local recurrence of advanced gastric cancer
Authors:Watanabe Fumiaki  Iwasaki Yoshiaki  Ohashi Manabu  Nunobe Souya  Iwagami Shirou  Takahashi Keiichi  Yamaguchi Tatsurou  Matsumoto Hiroshi  Yasutome Michiya
Affiliation:Dept. of Surgery, Metropolitan Komagome Hospital.
Abstract:
A 55-year-old woman, underwent a total gastrectomy with super extended lymphadectmy for type 4 gastric cancer 4 years ago, suffered a locoregional recurrence at the esophagojejunostomy. She was given S-1 with cisplatin for a treatment against the recurrent site. Although grade 2 leucocytopenia and grade 3 anorexia were observed, consecutive twenty five courses of the regimen were carried out with a dose modification of anticancer drugs, and home parentenral nutrition system was used for severe anorexia. She has been alive for more than 3 years since the start of the treatment with a good control of locoregional recurrent lesion, and no other apparent metastatic sites were observed.
Keywords:
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