他克莫司软膏治疗激素依赖性皮炎的疗效观察

目的：观察他克莫司软膏对激素依赖性皮炎的治疗作用。方法：将38例激素依赖性皮炎患者随机分为两组，治疗组外用他克莫司软膏，对照组外用抗过敏护肤品并加服中药及抗组胺药物，疗程为3周，治疗结束后比较症状、体征的改善情况。结果：疗程结束后两组患者的红斑、脱屑、瘙痒等症状均有明显改善，用药1周后单用他克莫司软膏治疗组疗效优于联合用药组（P〈0．05），3周后治疗组与对照组疗效无显著性差异（P〉0．05）。结论：他克莫司软膏治疗激素依赖性皮炎有较好的疗效。

The curative effect observation of Tacrolimus Ointment to corticosteroid-dependent dermitis

Objective To observe the effectiveness of Tacrolimus Ointment on corticosteroid-dependent dermitis. Methods 38 patients were divided into 2 groups randomly, 1 group treated with Tacrolimus Ointment, another treated with contra-sensitive toiletry and orally Chinese traditional medicine or antihistamine, compared the results. Results After the treatment, the symptoms of 2 groups improved obviously, the curative effect of the Tacrolimus group is better than the unite group in the first week(P<0.05); but there were no difference betweeb the 2 groups 3 weeks later(P>0.05). Conclusion In the treatment of corticosteroid-dependent dermitis, Tacrolimus Ointment is a perfect choice.