| 兔胸腹部爆炸伤后的血液浓缩及其可能机制 |
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| 引用本文： | 陈志强,王建民,李兵仓,张良潮,许川.兔胸腹部爆炸伤后的血液浓缩及其可能机制[J].微循环学杂志,2003,13(2):1-3. |
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| 作者姓名： | 陈志强 王建民 李兵仓 张良潮 许川 |
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| 作者单位： | 中国人民解放军第三军医大学大坪医院野战外科研究所,重庆,400042 |
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| 基金项目： | 中国人民解放军军队“十五”指令性课题 (0 1L0 60 ) |
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| 摘 要： | 目的 :探讨爆炸性冲击伤后血液浓缩的特点及其可能的机制。方法 :采用雷管所致兔爆炸性冲击损伤模型 ,以1 2 5I 白蛋白标记的方法 ,观察爆炸性冲击伤前后红细胞压积与血浆外渗情况。结果 :距爆源 2 0cm处的爆炸冲击波作用时 ,红细胞压积增加 14 .9% ,血浆丢失为对照的 5 .12倍 ,白蛋白漏出率为伤前的 1.3倍 ,左肺组织中残留放射性较对照组增加约 18% ,该点平均压力峰值为 174 .4kPa。结论 :爆炸冲击伤后的红细胞压积增加、血浆丢失是伤后微循环功能障碍的重要原因
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| 关 键 词： | 爆炸冲击伤 血液浓缩 血管通透性 |
| 修稿时间： | 2002年8月12日 |
The Blood Concentration After Explosive Injury on the Chest-abdomen of Rabbits and Its Possible Mechanism |
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| Chen Zhiqiang,Wang Jianmin,Li Bingcang,et al/Institute of Surgery Research,Daping Hospital,The Third Military Medical University of Chinese PLA,Chongqing.The Blood Concentration After Explosive Injury on the Chest-abdomen of Rabbits and Its Possible Mechanism[J].Chinese Journal of Microcirculation,2003,13(2):1-3. |
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| Authors: | Chen Zhiqiang Wang Jianmin Li Bingcang /Institute of Surgery Research Daping Hospital The Third Military Medical University of Chinese PLA Chongqing |
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| Institution: | Chen Zhiqiang,Wang Jianmin,Li Bingcang,et al/Institute of Surgery Research,Daping Hospital,The Third Military Medical University of Chinese PLA,Chongqing 400042 |
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| Abstract: | Objective: To explore the characteristics of blood concentration and its possible mechanism after explosive blast injury. Method: The model of explosive blast wounded on rabbits and the 125 I albumin dilution method have been used. Results: The explosive blast far from 20 cm can cause that hematocrit increased 14.9%, the loss of plasma is 5.12 fold compared with control group, the rate of 125 I albumin escaped is 1.3 fold compared with control group, the remained radiation in left lung tissue increased approximately 18%. On this site, average peak pressure of blast is 174.4 kPa. Conclusion: The explosive blast can cause hematocrit increase, plasma loss, albumin escaped from circulation, which may be important reason of microcirculation dysfunction after blast injury. |
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| Keywords: | Explosive blast injury Blood concentration Vascular permeability |
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