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DOUBLE INVASIVE FUNGAL INFECTION AND TYPHLITIS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA |
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| Authors: | Zekai Avci Bulent Alioglu Deniz Anuk Ozlem Yilmaz Ozbek Ozlem Kurt Azap Namik Ozbek |
| Affiliation: | 1. Baskent University Faculty of Medicine, Department of Pediatric Hematology, Ankara, Turkey;2. Baskent University Faculty of Medicine, Department of Pediatrics, Ankara, Turkey;3. Baskent University Faculty of Medicine, Department of Pediatric Allergy, Ankara, Turkey;4. Baskent University Faculty of Medicine, Department of Infection Disease and Clinical Microbiology, Ankara, Turkey |
| Abstract: | Invasive fungal infection is one of the major causes of morbidity and mortality in immunocompromised patients. The occurrence of two invasive fungal infections in one patient at the same time is quite rare. Here the authors report on two adolescent patients with acute lymphoblastic leukemia who developed combined invasive pulmonary aspergillosis and hepatosplenic candidiasis during chemotherapy. They were treated with liposomal amphotericin B, but one of them died due to massive pulmonary hemorrhage during recovery from neutropenia. |
| Keywords: | acute lymphoblastic leukemia hepatosplenic candidiasis invasive fungal infection invasive pulmonary aspergillosis neutropenic enterocolitis |