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Outcomes of Acute Renal Failure Patients Requiring Intermittent Hemodialysis
Authors:Savas Ozturk  Dilek Arpaci  Halil Yazici  Dilek Guven Taymez  Nilgun Aysuna  Alaattin Yildiz
Affiliation:1. Haseki Education and Research Hospital, Nephrology Unit, Istanbul, Turkeysavasozturkdr@yahoo.com;3. Istanbul University, Istanbul Medical Faculty, Internal Medicine, Fatih, Istanbul, Turkey;4. Istanbul University, Istanbul Medical Faculty, Internal Medicine, Division of Nephrology, Istanbul, Turkey
Abstract:The published studies on the prognosis of patients requiring intermittent hemodialysis (IHD) are scarce and have some conflicts. In this study, we retrospectively analyzed our data on ARF patients who were treated with IHD. A total of 192 (female: 85, 44.3%; male: 107, 55.7%) patients were included in the study. The mean age was 56.3 ± 17.1 years. In all, 48.9% of the patients were older than 60 years. The mean number of IHD sessions was 7.8 ± 8.0 per patient; 12.4% was due to prerenal causes, 76.8% was due to intrarenal causes, and 10.8% was due to postrenal causes. The leading indication of the IHD was uremic symptoms (46.8%). With the exclusion of hypertension, 72.4% of the patients had at least one systemic comorbidity. After treatment, 75.5% of the patients recovered, in contrast to 9.4% of patients who were transferred to chronic renal replacement programs and 15.1% who died during IHD period. Pre-dialytic serum creatinine (p?=?0.003) and albumin levels (p?=?0.016), total IHD session number per patient (p?=?0.003), and age (p?=?0.034) were the parameters that were related to high mortality in statistical analysis. Mortality was higher if the leading indication of IHD was biochemical disturbances (p?=?0.013). Diabetes mellitus did not influence mortality. Consequently, predialytic serum creatinine and albumin levels may be very important predictors of mortality. Patients in high-risk groups (older age, female sex, and low pre-dialytic creatinine and albumin levels) should be considered to be treated with slow continuous renal replacement methods.
Keywords:acute renal failure  intermittent hemodialysis  mortality  serum albumin  serum creatinine
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