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Rhabdomyolysis Caused by Gefitinib Overdose
Authors:Shohei Obayashi  Katsuyoshi Tomomatsu  Mika Urata  Jun Tanaka  Kyoko Niimi  Naoki Hayama  Tsuyoshi Oguma  Koichiro Asano  Yoko Ito
Affiliation:1.Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Japan
Abstract:
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are common therapeutic agents for EGFR mutation-positive advanced non-small-cell lung cancer. There has been no report of rhabdomyolysis caused by an overdose of EGFR-TKIs. We herein review the existing literature on the subject and report a rare case of rhabdomyolysis due to an overdose of gefitinib, an EGFR-TKI.
Keywords:EGFR-TKI   rhabdomyolysis   overdose
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