针刺治疗抑郁性神经症及对免疫功能的影响

目的 :观察针刺和黛力新 (Deanxit)治疗抑郁性神经症的疗效及其对免疫功能的影响。方法 :以CCMD 2 R为标准选取 41例抑郁性神经症患者 ,随机分为针刺组 2 1例及西药组 2 0例 ,针刺组以针刺治疗两个疗程共 2 0次 ,西药组服用黛力新治疗 2 0日 ,治疗前及疗程结束后以汉密顿抑郁量表HAMD评分 ,并检验疗程前后IL 2、IL 8值加以比较。结果 :每组组内治疗前后HAMD评分比较均有显著性差异 (P <0 0 1) ,两组治疗后评分比较无显著性差异 (P >0 0 5 ) ;每组组内IL 2、IL 8值治疗前后比较均有显著性差异 (P <0 0 1,P <0 0 5 ) ,同项目治疗后比较均无显著性差异 (P >0 0 5 )。结论 :针刺和黛力新均能有效治疗抑郁性神经症 ,其治疗原理可能与改善患者的免疫功能有关

Treatment of Depressive Psychosis with Acupuncture and Its Effect on Immunological Function

Objective: To observe the therapeutic effect of acupuncture in the treatment of depressive psychosis and to analyze its influence on the immunological function. Methods: A total of 41 depression patients were randomized in to acupuncture group ( n =21) and medication group ( n =20). In acupuncture group, Taiyang (EX-HN 5), Yintang (EX-HN 3), Baihui (GV 20), Neiguan (PC 6), Z usanli (ST 36), etc. were punctured and stimulated electrically with an electroa cupuncture (EA) therapeutic apparatus for 20 min. In medication group, patients were asked to take Deanxit ta blets. Results: After 20 days' treatment, the scores of Hamilton rating scale for depression (HAMD) of two groups lowered significantl y compared with their own pre-treatment ( P <0.01); an d comparison between two groups showed that there was no significant difference between them in HAMD scores ( P >0.05). Following treatment, blood IL-2 and IL-8 contents decreased considerably ( P <0.05～ 0.01) , which had not sign ificant differences between two groups( P >0.05). Conclusion: Both acupuncture therapy and medication work well in the treatment of depressive psychosis and their ther apeutic effects may be closely related to the decline of blood IL-2 and IL-8 l evels.