| 光动力疗法治疗恶性实体瘤的临床观察 |
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| 引用本文： | 李毅,杨镇洲,王佳,郑珊,王阁,王东.光动力疗法治疗恶性实体瘤的临床观察[J].解放军医学杂志,2005,30(11):975-977. |
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| 作者姓名： | 李毅 杨镇洲 王佳 郑珊 王阁 王东 |
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| 作者单位： | 400042,重庆,第三军医大学大坪医院野战外科研究所肿瘤中心;400042,重庆,第三军医大学大坪医院野战外科研究所肿瘤中心;400042,重庆,第三军医大学大坪医院野战外科研究所病理科 |
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| 摘 要： | 目的观察和评价光动力疗法（PDT）治疗恶性肿瘤的临床疗效。方法对20例各期不同类型恶性肿瘤患者行PDT／以PDT治疗为主的综合治疗，随访观察和分析其临床疗效。结果20例患者PDT治疗后随访1～6个月，其中3例早期肿瘤患者局部肿瘤完全消失，随访期无复发；17例晚期患者PDT治疗后CR9例，PR8例。20例患者中3例死亡，死因与PDT无关。结论PDT对早期肿瘤有根治效果，对晚期肿瘤的局部病灶也有较好的近期疗效，PDT是目前治疗恶性肿瘤可选择的一种有效手段。
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| 关 键 词： | 光动力疗法 恶性肿瘤 激光 |
| 收稿时间： | 2005-07-18 |
| 修稿时间： | 2005-08-28 |
Clinical effect of photodynamic therapy in the treatment of malignant tumor |
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| Li Yi, Yang Zhenzhou, Wang Jia et al..Clinical effect of photodynamic therapy in the treatment of malignant tumor[J].Medical Journal of Chinese People's Liberation Army,2005,30(11):975-977. |
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| Authors: | Li Yi Yang Zhenzhou Wang Jia |
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| Institution: | Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China |
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| Abstract: | Objective To observe and evaluate clinical therapeutic effect of photodynamic therapy (PDT) on malignant tumor. Methods 20 patients of malignant tumors of different nature and different stages were subjected to PDT or PDT-predominant comprehensive therapy. All the patients were followed-up, and the clinical results were analyzed. Results Among these patients, 3 tumors at early stage showed complete remission (CR), and no relapse was found in the follow-up period. Among the 17 cases with tumors in advanced stage, CR was seen in 9 cases, PR in 8, and 3 patients died of causes other than PDT after 1-6 months of follow-up. Conclusion PDT shows a curative effect on malignant tumors in early stage, and fairly good therapeutic effect on those in advanced stage. It is one of the optional treatments for malignant tumors. |
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| Keywords: | photodynamie therapy malignant neoplasms laser |
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