沈阳市1992～2006年女性乳腺癌死亡趋势分析

目的:探讨1992～2006年沈阳市女性乳腺癌死亡率水平及变化趋势、特点。方法:用SAS6.12软件对乳腺癌死亡率、死亡构成等指标进行分析,并进行χ2趋势检验。结果:沈阳市女性乳腺癌死亡率呈上升趋势,15年间上升了57.37%,年均增长速度为3.29%。乳腺癌年均死亡率为9.11/10万,标化死亡率为6.69/10万。乳腺癌在恶性肿瘤中的顺位从2006年开始,由原来的第5位上升至第3位。乳腺癌死亡率从35～岁组开始随年龄增加而明显上升,年龄越大,死亡率越高。45～64岁年龄段乳腺癌死亡率随时间推移,呈明显上升趋势,经χ2趋势检验,有高度统计学意义(χ2=22.43,P<0.0001)。结论:沈阳市乳腺癌死亡率上升速度较快,应重点加强45～64岁年龄段女性乳腺癌的防治。

Breast cancer mortality tendency among women from 1992 to 2006 in Shenyang

Objective:To explore breast cancer mortality tendency and patterns among women in Shenyang.Methods:Mortality and constitute ratio of breasts cancer and other measurements were analyzed using χ2 test with the help of SAS6.12 software.Results:Breast cancer mortality rate among women in Shenyang city increased 57.37% during past 15 years,the mortality increased 3.29% per year.Yearly average breast cancer mortality was 9.11 per 100 000 and its age-standardized mortality was 6.69 per 100 000.From 2006 breast cancer mortality increased from top 5 to top 3 among malignant tumors.Breast cancer mortality increased remarkably from age 35~years,the older,the higher mortality.However,the increasing mortality tendency of breast cancer with time was limited to women aged 45~64 years,and it had highly statistical significance(χ2=22.43,P<0.000 1).Conclusion:Breast cancer mortality increases rapidly in Shenyang city.It indicates women aged 45~64 years are the target population of prevention.