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| The expression of TRPA1 mRNA in the rat brain | |
| 引用本文： | Peng Du,Shua Li,Jinyu Zheng,Zhi-yuan Yu,Minjie Xie,Wei Wang. The expression of TRPA1 mRNA in the rat brain[J]. 南京医科大学学报(自然科学版), 2006, 20(4): 225-228 |
| 作者姓名： | Peng Du Shua Li Jinyu Zheng Zhi-yuan Yu Minjie Xie Wei Wang |
| 作者单位： | [1]Department of Neurology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China [2]Shanghai Institute of Neuroscience, Shanghai 200030,China; [3]Department of Pathology,Drum Tower Hospital, Nanjing University, Nanjing210008 ,China |
| 基金项目： | 科技部重点项目;教育部高校新世纪杰出人才项目 |
| 摘 要： | Objective： To investigate the distribution of TRPA1 （one kind of the TRP-like ion channel family） channel in the hippocampus and cerebral cortex of rat. Methods： RT-PCR was used to amplify the fragment of TRPA1 in the DRG （dorsal root ganglion）, hippocampus and cerebral cortex of adult SD rat. In situ hybridization staining was used to show the distribution of TRPA1 mRNA in the hippocampus and cerebral cortex of adult rat brain. Results： Both RT-PCR and in situ hybridization staining showed that TRPA1 mRNA was expressed in hippocampus and cerebral cortex of the adult rat brain. Conclusion： Our results suggest that there is expression of TRPA1 mRNA both in the hippocampus and cerebral cortex of the adult rat brain. |
| 关 键 词： | 基因表达 脑损伤 海马 脑皮质 |
| 收稿时间： | 2006-02-27 |
The expression of TRPA1 mRNA in the rat brain |
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| Peng Du,Shua Li,Jinyu Zheng,Zhi-yuan Yu,Minjie Xie,Wei Wang. The expression of TRPA1 mRNA in the rat brain[J]. Acta Universitatis Medicinalis Nanjing, 2006, 20(4): 225-228 | |
| Authors: | Peng Du Shua Li Jinyu Zheng Zhi-yuan Yu Minjie Xie Wei Wang |
| Abstract: | Objective:To investigate the distribution of TRPA1(one kind of the TRP-like ion channel family)channel in the hippocampus and cerebral cortex of rat.Methods:RT-PCR was used to amplify the fragment of TRPA1 in the DRG(dorsal root ganglion),hippocampus and cerebral cortex of adult SD rat.In situ hybridization staining was used to show the distribution of TRPA1 mRNA in the hippocampus and cerebral cortex of adult rat brain.Results:Both RT-PCR and in situ hybridization staining showed that TRPA1 mRNA was expressed in hippocampus and cerebral cortex of the adult rat brain.Conclusion:Our results suggest that there is expression of TRPA1 mRNA both in the hippocampus and cerebral cortex of the adult rat brain. |
| Keywords: | TRPA1 RT-PCR in situ hybridization hippocampus cerebral cortex rat |
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