| 端粒酶活性检测在消化道恶性肿瘤诊断中的应用价值研究 |
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| 引用本文： | 赵跃亭,陈书恩,许培仁,王瑞华,张国民,任学群,刘红林. 端粒酶活性检测在消化道恶性肿瘤诊断中的应用价值研究[J]. 河南大学学报(医学版), 1999, 0(1) |
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| 作者姓名： | 赵跃亭 陈书恩 许培仁 王瑞华 张国民 任学群 刘红林 |
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| 作者单位： | 开封医专附属淮河医院!开封475000 |
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| 基金项目： | 开封市自然科学基础研究项目 |
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| 摘 要： | 目的：探讨端粒酶活性在消化道恶性肿瘤诊断中的应用价值。方法：使用改良的TRAP-银染法。结果：检测83例消化道肿瘤标本端粒酶活性,其中食道癌31例,阳性29例;胃癌30例,阳性24例;大肠癌22例,阳性20例。结论：改良TRAP-银染法检测消化道恶性肿瘤端粒酶活性对消化遣恶性肿瘤的诊断、预后及指导治疗有重要的价值。
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| 关 键 词： | 端粒酶 改良TRAP-银染法 消化道恶性肿瘤 |
Study on the applicable value of telomerase activity detection in diagnosing malignant cancinoma of digestive system |
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| Zhao Yaoting, Chen Shu''''en, Xu Peiren, et al. Study on the applicable value of telomerase activity detection in diagnosing malignant cancinoma of digestive system[J]. Journal of Henan University, 1999, 0(1) |
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| Authors: | Zhao Yaoting Chen Shu''''en Xu Peiren et al |
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| Abstract: | Objectie:To probe into the applicable value of telomerase actvity of esophageal cancer, gastric cancer and colorectal cancer by using silver staining telomerase repea amplification protocol (TRAP). Results: Among 83 cases with malignant carcinoma of digestive system the positive rate of telomerase activity was 93 .5% (29/31)in esophaseal cancer, 80. 0% (24/30) in gastric cancer,90. 9% (20/22) in colorectal cancer. Conclusion: Detection telomerase activity in patients with malignant carcinoma of digestive system could hele to evalute clinical patients and contribute to their treatment. |
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| Keywords: | telomerase silver staining-TRAP malignant carcinoma of digestive system |
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