5 816株病原菌或机会致病菌耐药性监测

目的 探讨临床用药对细菌耐药菌株产生的影响。指导临床合理使用抗生素。方法 监测常见病菌及机会致病菌耐药性，对３年间由临床送检标本检出细菌的药敏结果进行统计分析，结果 共检出细菌５８１６株，其中Ｇ＾＋球菌２１７２株（３７．３４％）对青霉素，苯唑青霉素耐药率较高（〉８０％）对丁胺卡那霉素，头孢唑啉，头孢哌酮较敏感，而对万古霉素，舒普深极度敏感，头孢唑啉，头孢哌酮较敏感，而对万古霉素，舒普深极度敏感。Ｇ

Testing drug resistance of 5 816 strains or opportunistic pathogen

Objective To study the influence of drug use on the development of durg resistant strains to help appropriate selection of antibiotics in clinical practice. Methods We collected and isolated 5816 strains of bacteria. Bacteria susceptibility testing was carried out using Kirby Bauer method. Results Among 5816 strains of common pathogen, 2172 strains(37 34%) were gram positive cocci, and 3325 strains(57 17%) gram negative bacilli. The former showed high resistant rate(>80%) to penicillin and oxacillin, but they were sensitive to amikacin, cefazolin and cefoperzone, and vancomycin and sulperzone were the best. The garm negative bacilli were resistant to norfloxacin and the first generation cephalosporins, but they were sensitive to amikacin and the third generation cephalosporins. The most sensitive antibiotic was sulperzone. Conclusion The therapeutic time of antibiotics directly affects the development of drug resistant strains. Clinical doctors should select antibiotics according to the sensitivity of the drugs.