| 头孢噻肟钠皮试液稳定性考察 |
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| 引用本文： | 杨建华,王松芝,胡君萍,曼苏尔.头孢噻肟钠皮试液稳定性考察[J].新疆医科大学学报,2001,24(4):359-360. |
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| 作者姓名： | 杨建华 王松芝 胡君萍 曼苏尔 |
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| 作者单位： | 1. 新疆医科大学,附属肿瘤医院药剂科,新疆,乌鲁木齐,830011
2. 新疆医科大学,药学院药分教研室,新疆,乌鲁木齐,830054 |
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| 摘 要： | 目的：考察头孢噻肟钠皮试液稳定性。方法：采用经典恒温加速试验法及留样观察法，考察头孢噻肟钠皮试液外观、pH值及紫外光谱的变化，用紫外分光光度法测定头孢噻肟钠的含量。结果：恒温加速试验25℃时预测其有效期为3d；留样观察试验装置1周，药品降解9．8％。结论：本品稳定性较差，室温避光保存不宜超过3d。
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| 关 键 词： | 头孢噻肟钠皮试液 紫外分光光度法 药品稳定性 头孢菌素 |
| 文章编号： | 1009-5551(2001)04-0359-02 |
| 修稿时间： | 2000年9月14日 |
Investigation of the stability of cefotaxime sodium intracutaneous injection |
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| YANG Jian-hua,WANG Song-zhi,HU Jun-ping,et al.Investigation of the stability of cefotaxime sodium intracutaneous injection[J].Journal of Xinjiang Medical University,2001,24(4):359-360. |
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| Authors: | YANG Jian-hua WANG Song-zhi HU Jun-ping |
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| Abstract: | Objective: To study the stability of cefotaxime sodium intracutaneous injection. Methods: The stability, appearance,pH and UV absorption spectrum was studied by accelerated testing and long-term testing. Results: There were no significant changes in pH and appearance. Cefotaxime sodium concentration droped to 90.2% at room temperature after one week. Conclusions: The stability of cefotaxime sodium intracutaneous injection is not good. Under the storage conditions of room temperature and avoiding sunlight, the favourable storage life should not be more than 3 days. |
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| Keywords: | cefotaxime sodium intracutaneous injection stability Uv-spectrophotometry |
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