| 三白草体外抗氧化活性 |
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| 引用本文： | 尹震花,顾雪竹,张一冰,王佳佳,康文艺.三白草体外抗氧化活性[J].中国实验方剂学杂志,2012,18(4):99-102. |
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| 作者姓名： | 尹震花 顾雪竹 张一冰 王佳佳 康文艺 |
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| 作者单位： | 1. 河南大学中药研究所,河南开封,475000
2. 中国中医研究院中药研究所,北京 ,100700 |
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| 基金项目： | 河南省科技厅重点攻关项目(102102310019) |
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| 摘 要： | 目的:研究三白草体外抗氧化活性.方法:采用清除二苯代苦味酰基(DPPH)自由基和2,2′-连氨-(3-乙基苯并噻唑啉-6-磺酸)二氨盐](ABTS)自由基测定法,对三白草提取物抗氧化活性进行评价.结果:正丁醇提取物清除DPPH自由基(IC50=16.94)的能力比BHT清除能力(IC50=18.71 mg·L-1)强,弱于阳性对照PG和BHA清除DPPH自由基的能力(IC50分别为0.89,3.2mg· L-1)；清除ABTS自由基的能力(IC50=12.90 mg·L-1)弱于阳性对照PG和BHA清除ABTS自由基的能力(IC50分别为0.81,1.95 mg·L-1),比阳性对照BHT( IC50为7.72mg· L-1)清除ABTS自由基的能力略弱；石油醚提取物和乙酸乙酯提取物清除DPPH和ABTS自由基的能力均比阳性对照PG,BHT,BHA清除DPPH和ABTS自由基的能力弱.结论:三白草正丁醇提取物有抗氧化活性.
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| 关 键 词： | 三白草 抗氧化活性 二苯代苦味酰基 2 2′-连氨-(3-乙基苯并噻唑啉-6-磺酸)二氨盐 |
Antioxidant Activity of Saururus chinensis in vitro |
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| YIN Zhen-hu,GU Xue-zhu,ZHANG Yi-bing,WANG Jia-jia and KANG Wen-yi.Antioxidant Activity of Saururus chinensis in vitro[J].China Journal of Experimental Traditional Medical Formulae,2012,18(4):99-102. |
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| Authors: | YIN Zhen-hu GU Xue-zhu ZHANG Yi-bing WANG Jia-jia and KANG Wen-yi |
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| Institution: | Institute of Chinese Materia, Henan University, Kaifeng 475000, China;Institute of Chinese Materia Medica, Traditional Chinese Medical Research Institute, Beijing 100700, China;Institute of Chinese Materia, Henan University, Kaifeng 475000, China;Institute of Chinese Materia, Henan University, Kaifeng 475000, China;Institute of Chinese Materia, Henan University, Kaifeng 475000, China |
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| Abstract: | Objective: To study the antioxidant activity of Saururus chinensis in vitro. Method: The antioxidant activities of S. chinensis were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and diamonium salt (ABTS) radical scavenging. Result: n-Butanol extract from S. chinensis showed higher DPPH radical scavenging activity (IC50=16.94 mg·L-1) than that of BHT (IC50=18.71 mg·L-1) as positive control, and lower than that of PG and BHA (IC50=0.89, 3.2 mg·L-1) as positive control. ABTS radical scavenging activity (IC50=12.90 mg·L-1) showed much lower than that of than PG and BHA (IC50= 0.81, 1.95 mg·L-1) as positive controls, and slightly lower than that of BHT (IC50=7.72 mg·L-1). Petroleum ether extract and ethyl acetate extract showed lower DPPH and ABTS radical scavenging activity than that of PG, BHT and BHA. Conclusion: n-Butanol extract from S. chinensis had antioxidant activity. |
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| Keywords: | Saururus chinensis antioxidant activity DPPH ABTS |
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