| 细胞因子诱导的杀伤细胞治疗恶性淋巴瘤的研究进展 |
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| 引用本文： | 贺白. 细胞因子诱导的杀伤细胞治疗恶性淋巴瘤的研究进展[J]. 白血病．淋巴瘤, 2014, 23(12): 760-764 |
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| 作者姓名： | 贺白 |
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| 作者单位： | 213003,江苏省常州市第一人民医院肿瘤生物诊疗中心 |
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| 摘 要： | 细胞因子诱导的杀伤细胞（CIK细胞）是一群体外诱导的以CD3＋ CD56＋T细胞为主的异质细胞群,具有效应CD8＋T细胞的T细胞受体特异性和非主要组织相容性复合体（MHC）限制性抗肿瘤活性的特点.国内外研究结果表明CIK细胞对恶性淋巴瘤有明显的抗肿瘤效应,且有很好的耐受性.提示CIK细胞治疗对于恶性淋巴瘤患者尤其是不能耐受放化疗的淋巴瘤患者具有重要价值.
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| 关 键 词： | 恶性淋巴瘤 细胞因子诱导的杀伤细胞 树突状细胞 |
Research progress of cytokine-induced killer cell-based immunotherapy for malignant lymphoma |
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| He Bai. Research progress of cytokine-induced killer cell-based immunotherapy for malignant lymphoma[J]. Journal of Leukemia & Lymphoma, 2014, 23(12): 760-764 |
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| Authors: | He Bai |
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| Affiliation: | . (Center of Tumor Biological Treatment, the First People＇ s Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou 213003, China) |
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| Abstract: | Cytokine-induced killer cells （CIK cells） are a group of CD3＋ CD56＋ T cell-based heterogeneous cells generated in vitro,with T-cell receptor （TCR） specificity of CD8＋ T cells and anti-tumor activity of non-restrictive major histocompatibility complex （MHC）.Recent studies indicated that vaccination with CIK cells induced strong anti-tumor activity in the treatment of malignant lymphoma.These researches show that CIK cell-based immunotherapy has the important values for patients with malignant lymphoma. |
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| Keywords: | Malignant lymphoma Cytokine-induced killer cell Dendritic cell |
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