依达拉奉治疗急性脑梗死的疗效观察

目的:观察依达拉奉对急性脑梗死的疗效.方法:对我院神经内科住院60例发病48小时以内的急性脑梗死患者,随机分为两组,治疗组30例,对照组30例,14天为一个疗程;分别在治疗前、治疗后1周、治疗后2周评估其神经功能缺损程度和日常生活自我照顾能力.结果:治疗组总有效率83.33%,对照组总有效率56.67%,差异具有显著性(P＜0.05).治疗组神经功能缺损程度和日常生活自我照顾能力在治疗后1周与治疗前比较无显著差异,但治疗2周差异具有显著性(P＜0.05).结论:依达拉奉治疗急性脑梗死疗效好,安全性高.

Edaravone treatment of acute cerebral infarction

Objective: To investigate therapeutic effect of edaravone in acute cerebral infarction.Methods: 60 inpatients with acute cerebral infarction within 48 h after the onset in department of neurology of our neurology were randomly divided into control group(30 cases) and treatment group(30 cases) treated with edaravone(30 mg N.S.100 mL iv.gtt,bid) for 14 days.The neurological deficits and daily living skills such as self-care ability(SLA) were assessed one and two weeks after treatment.Results: The efficacy rate of treatment group were higher than that of control group(83.33% vs 56.67%,P<0.05).Neurological deficits and the SLA of were also significantly improved in treatment group(vs control group,P<0.05),although the difference was not obvious after 1 week.Conclusion: Edaravone was safe and efficient in the treatment of acute cerebral infarction.