| 微卫星不稳定性与结直肠癌的研究进展 |
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| 引用本文： | 孙伟杰,彭海霞. 微卫星不稳定性与结直肠癌的研究进展[J]. 胃肠病学, 2020, 0(1): 55-58 |
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| 作者姓名： | 孙伟杰 彭海霞 |
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| 作者单位： | 上海交通大学医学院附属同仁医院内窥镜室 |
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| 基金项目： | 上海市科学技术委员会基金(18ZR1434900)。 |
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| 摘 要： | 结直肠癌(CRC)在全球范围内的发病率和死亡率均较高.目前研究认为CRC是一种由各种原因造成的遗传不稳定性长期积累、共同作用所致的异质性疾病,微卫星不稳定性(MSI)是其中的主要途径之一.本文就MSI与CRC的研究进展作一综述.
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| 关 键 词： | 结直肠肿瘤 微卫星不稳定性 治疗 |
Advances in Research on Correlation of Microsatellite Instability With Colorectal Cancer |
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| SUN Weijie,PENG Haixia. Advances in Research on Correlation of Microsatellite Instability With Colorectal Cancer[J]. Chinese Journal of Gastroenterology, 2020, 0(1): 55-58 |
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| Authors: | SUN Weijie PENG Haixia |
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| Affiliation: | (Digestive Endoscopy Center,Tongren Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,200336) |
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| Abstract: | Colorectal cancer(CRC)has a high morbidity and mortality rate worldwide.Current studies indicate that CRC is a heterogeneous disease caused by long-term accumulation and joint action of genetic instability caused by various reasons.Microsatellite instability(MSI)is one of the main pathways.This article reviewed the advances in research on correlation of MSI with CRC. |
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| Keywords: | Colorectal Neoplasms Microsatellite Instability Therapy |
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