神经内科重症监护病房医院获得性鲍曼不动杆菌肺炎30例临床分析

目的：分析神经内科重症监护病房（ NICU）医院获得性鲍曼不动杆菌肺炎发生的特点及防治措施。方法采取前瞻性研究的方法，对NICU发生医院感染患者的临床资料进行分析。结果 NICU医院获得性鲍曼不动杆菌肺炎感染发生率为9.04％。鲍曼不动杆菌肺炎患者多合并有各种慢性疾病和各种侵袭性诊疗；脑卒中患者合并鲍曼不动杆菌肺炎比率较高。鲍曼不动杆菌除了对碳青霉烯类、头孢哌酮舒巴坦抗菌药物有较高的敏感性外，对头孢菌素类、氨基甙类和氟喹诺酮类等抗菌素均耐药严重。结论 NICU鲍曼不动杆菌对抗菌药物的耐药率较高且呈多重耐药态势，医务人员应当严格遵守无菌技术操作规程，合理选择抗生素，并加强对鲍曼不动杆菌耐药的监测。

Clinical analysis of 30 cases nosocomial acquired pneumonia of acinetobacter baumanii in neurology intensive care unit

Objetcive To analyze the occurring characteristic and preventive measures of nosocomial acquired pneumonia of acinetobacter baumanii（Ab）in neurology intensive care unit（NICU）.Metho ds The data of nosocomial infection for the medical records in NICU were analyzed by prospective monitoring studies.Results Noso-comial acquired pneumonia of Ab occurred in 9.04%patients admitted to the NICU.The most patients with nosocomial acquired pneumonia of Ab had chronic diseases and underwent many kinds of invading operation.The rate of nosocomial acquired pneumonia of Ab in stroke patients were higher.In the vitro drug susceptibility test,only the sensitive rates of carbapenems and cefoperazone sulbactam were higher, and Ab were multi-resistant to cephalosporins, aminoglycosides and fluoroquinolone antibiotics.Conclusion The drug resistance of Ab is severe and multi-resistant to antibiotics, so it is necessary to obey aseptic operation rule strictly, use the antibiotics rationally and strengthen monitoring of drug resistance of Ab.