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动脉粥样硬化血管重塑的认识与研究进展
引用本文:黄广勇,卢才义.动脉粥样硬化血管重塑的认识与研究进展[J].心血管病学进展,2005,26(6):589-592.
作者姓名:黄广勇  卢才义
作者单位:中国人民解放军总医院老年心血管病研究所,北京,100853
摘    要:血管重塑是影响动脉粥样硬化及球囊损伤后血管管腔面积的主要决定因素,血管重塑是在血流动力学、内皮功能及炎症等多因素参与下进行的,涉及到细胞的生长、凋亡、迁移及细胞外基质的合成、降解和重新排布,正性重塑比负性重塑伴随更明显的炎症和斑块易损性,而球囊损伤后的血管重塑以负性收缩性重塑为特征。

关 键 词:动脉粥样硬化  血管重塑
文章编号:1004-3934(2005)06-0589-04
收稿时间:2005-04-11
修稿时间:2005年4月11日

Atherosclerotic Arterial Remodeling
HUANG Guang-yong,LU Cai-yi.Atherosclerotic Arterial Remodeling[J].Advances in Cardiovascular Diseases,2005,26(6):589-592.
Authors:HUANG Guang-yong  LU Cai-yi
Institution:Institute of Geriatric Cardiology,Chinese PLA General Hospital, Beijing 100853, China
Abstract:Arterial remodeling is the major determinant of artery luminal area after atherosclerosis or balloon dilation.The process of arterial remodeling may involve hemodynamic,endothelial function and inflammation,which relate to growth,apoptosis,shift of cell as well as breakdown,build up and rearrange of extracellular matrix.Positive remodeling is associated with more inflammation response and vulnerable plaque.While balloon injury artery is characterized by negative remodeling.
Keywords:Atherosclerosis  Arterial remodeling
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