肾移植供者及受者肝炎等病毒和螺旋体感染的调查

目的 调查肾移植供、受者肝炎病毒及其他病毒感染和螺旋体感染的情况，研究其感染与移植术后人／肾存活率的关系。方法 对供者及移植受者群进行乙型肝炎（HBV）、丙型肝炎（HCV）、庚型肝炎病毒（HGV）及巨细胞病毒（CMV）、EB病毒、单纯庖疹病毒（HSV）、艾滋病病毒（HIV）、梅毒螺旋体（RPR）的调查。结果 361名供者中，感染HBV者8.6%，感染HCV者2.5％，感染HGV者0.6％；231名供者中，CMV－IgM阳性者16.9％，EB－IgM阳性者11.7％，HSV－IgV阳性者16.0％，HIV病毒携带者1名，RPR－IgM阳性者2名。300例移植受者中，HBV感染率为68.7％，HCV感染率为34.7％，HBV合并HCV感染率为25.0％，HGV、HBV合并HCV感染率为12.5％，CMV－IgM阳性者49.0％，EB－IgM阳性者32.7％，HSV－IgM阳性者42.0％，无HIV携带者及RPR－IgM阳性者49.0％，EB－IgM阳性者32.7％，HSV-IgM阳性者42.0％，无HIV携带者及RPR－IgM阳性者。结论 供者群及受者本身的术前病毒感染状态对移植者术后是否发生病毒感染至关重要。

The investigation on hepatitis virus and spirochete infection in renal transplant donors and recipients

Objective To investigate the infection of hepatitis virus and spirochete in renal transplant donors and recipients to study the relationship between infection and human/kidney survival rate following renal transplantation. Methods A total of 361 donors and 300 recipients were investigated on infection of HBV, HCV, HGV, CMV, EBV, HSV, HIV and RPR. Results Of the 361 donors, 31 cases ( 8.6 ?%), 9 cases ( 2.5 ?%) and 2 cases ( 0.6 ?%) were found having HBV, HCV, HGV infection respectively. In the 231 recipients, the percentage of CMV, EBV, HSV, HIV and RPR carriers was 16.9 ?%, 11.7 ?%, 16.0 ?%, 0.4 ?% and 0.8 ?% respectively. Among the 300 grafting recipients, the infective rate of HBV, HCV and HBV plus HCV was 68.7 ?%, 34.7 ?% and 25.0 ?% respectively. Forty patients were randomly selected from the 300 patients, it was found that 10 ( 25.0 ?%) patients were positive for anti HGV, 10 ( 25.0 ?%) for HGV and HBV, 5 ( 12.5 ?%) for all HGV, HBV and HCV. The percentage of CMV, EBV, HSV, HIV, RPR carriers among the 300 recipients was 49.0 ?%, 32.7 ?%, 42.0 ?%, 0 and 0.3 ?% respectively. Conclusion Viral infectious status of the donors and recipients before operation might contribute to the occurrence of viral infection in the recipients after transplantation.