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| p16^INK4a基因与子宫颈癌及其癌前病变关系的研究进展 | |
| 引用本文： | 张彩霞,段仙芝,岑尧. p16^INK4a基因与子宫颈癌及其癌前病变关系的研究进展[J]. 内蒙古医学杂志, 2009, 41(5): 583-586 |
| 作者姓名： | 张彩霞 段仙芝 岑尧 |
| 作者单位： | 内蒙古自治区医院妇产科,内蒙古,呼和浩特,010017 |
| 摘 要： | 随着分子生物学技术的飞速发展,人们越来越认识到抑癌基因在肿瘤的发生发展过程中具有重要作用。p16^INK4a是人们发现的第一个直接参与细胞周期调控的抑癌基因。它在宫颈癌和癌前病变阶段表现为过表达,可作为一种肿瘤标志物用于宫颈癌及癌前病变的临床筛查及诊断中。 |
| 关 键 词： | p16INK4a宫颈癌 癌前病变 |
Study on The Relationship Between p16~(INK4a) and Cervical Cancer |
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| ZHANG Cai-xia,DUAN Xian-zhi,CEN Yao. Study on The Relationship Between p16~(INK4a) and Cervical Cancer[J]. Inner Mongolia Medical Journal, 2009, 41(5): 583-586 | |
| Authors: | ZHANG Cai-xia DUAN Xian-zhi CEN Yao |
| Affiliation: | Department of Gynecology and Obstetrics;Inner Mongolia Hospital;Huhhot 010017 China |
| Abstract: | With the development of molecular biology,it is knowed that anti-ongene played important role in the genesis and development of tumors.p16INK4a is the first known anti-oncogene involved in regulating cell cycle.It shows overexpression in cervical cancer and precancerous lesions.p16INK4a may be used in clinical screening and diagnosis of cervical cancer and precancerous leisions. |
| Keywords: | p16INK4a Cervical cancer Precancerous lesion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |