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Pulmonary small cell carcinoma associated with sarcoid reactions: Report of a case
Authors:Mitsuhiro Kamiyoshihara  Toshikazu Hirai  Osamu Kawashima  Susumu Ishikawa  Yasuo Morishita
Affiliation:(1) Department of Surgery, National Sanatorium, Nishi-Gunma Hospital, 377-0027 Shibukawa, Gunma, Japan;(2) Second Department of Surgery, Gunma University School of Medicine, 371-0034 Maebashi, Gunma, Japan;(3) Nakazato-mura National Health Insurance Clinic, 430-1 Kagahara, Nakazatomura, Tano-gun, 370-1602 Gunma, Japan
Abstract:
A 45-year-old male was admitted to our hospital for investigation of a nodular shadow in segment 5 of the right lung on a chest computed tomogram. A right middle lobectomy with mediastinal lymph node dissection was performed under a diagnosis of lung cancer, and histologic examination confirmed small cell carcinoma. There were sarcoid reactions in the resected lymph nodes and the lung parenchyma, but no signs of systemic sarcoidosis were evident. Sarcoid reactions are rarely observed in the regional lymph nodes draining malignant tumors. Moreover, while they are most common in squamous cell carcinoma of the lung, they extremely rare in small cell carcinoma. To our knowledge, this is only the third report of this unusual entity in the English and Japanese literature.
Keywords:sarcoid reaction  small cell carcinoma  lung cancer
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