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吡美莫司联合白芍总苷治疗面部糖皮质激素依赖性皮炎生活质量及疗效研究
引用本文:莫均均.吡美莫司联合白芍总苷治疗面部糖皮质激素依赖性皮炎生活质量及疗效研究[J].中国中西医结合皮肤性病学杂志,2011,10(5):291-293.
作者姓名:莫均均
作者单位:江苏省大丰市人民医院,大丰,224100
摘    要:目的观察吡美莫司软膏联合白芍总苷治疗面部糖皮质激素依赖性皮炎疗效。方法 73例患者随机分为两组,对照组36例,治疗组37例。所有患者均面部负离子喷雾,2次/d,持续2周。对照组外用1%吡美莫司软膏,早晚各1次;治疗组在对照组治疗基础上给予口服白芍总苷胶囊0.6g/次,3次/d,两组均用1个月。分别在治疗前、治疗后2周和4周,采用皮肤病学生活质量指数(DLQI)问卷调查,测量皮肤疾患对生活的影响,并对两组患者的临床疗效进行评价。结果治疗前两组患者生活质量评分无统计学差异。治疗2周、4周后,治疗组生活质量的改善程度均显著高于对照组(P<0.05)。治疗组的有效率为81.08%,显著高于对照组的有效率(33.33%),差异具有统计学意义(P<0.05)。结论吡美莫司软膏联合白芍总苷治疗面部糖皮质激素依赖性皮炎效果肯定,值得在临床上使用。

关 键 词:吡美莫司  白芍总苷  面部糖皮质激素依赖性皮炎  生活质量指数

Research of Pimecrolimu Combined with Total Glycosides of Paeony on the Life Quality and Efficacy of Facial Corticosteroid Addictive Dermatitis
Mo Jun-jun.Research of Pimecrolimu Combined with Total Glycosides of Paeony on the Life Quality and Efficacy of Facial Corticosteroid Addictive Dermatitis[J].Chinese J of Dermatovenerology Integr Tradit and West Med,2011,10(5):291-293.
Authors:Mo Jun-jun
Institution:Mo Jun-jun People Hospital of DaFeng City in Jiangsu Province,Dafeng 224100,China
Abstract:Objective To investigate the efficacay of Pimecrolimu combined with total glycosides of paeony(TGP) on treating the facial corticosteroid addictive dermatitis(FCAD).Methods 73 patients were randomly divided into two groups,36 cases in control group and 37 cases in treatment group.All patients were treated with maxillofacial anion aerosol twice a day,consecutively lasted for 14 days.Control group was topically treated with 1% pimecrolimu cream twice daily,and treatment group was orally added with TGP capsule...
Keywords:Pimecrolim  total glycosides of paeony  facial corticosteroid addictive dermatitis  life quality index  
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