首页 | 本学科首页   官方微博 | 高级检索  
     

依拉普利与厄贝沙坦联用对原发性高血压患者左室肥厚的逆转作用
引用本文:谢梦,王远方,徐敏,涂清源,王梅. 依拉普利与厄贝沙坦联用对原发性高血压患者左室肥厚的逆转作用[J]. 贵州医药, 2004, 28(7): 593-595
作者姓名:谢梦  王远方  徐敏  涂清源  王梅
作者单位:贵州省遵义医院老年病科,563002;贵州省遵义医院心内科,563002;成都铁路局遵义铁路医院内科
摘    要:目的对比研究依拉普利与厄贝沙坦联用对原发性高血压(EH)患者左室肥厚(LVH)的逆转作用。方法将92例EH伴LVH患者随机分为A组(厄贝沙坦150nlg·d-1)46例,B组(依拉普利5-10mg·d-1与厄贝沙坦75mg·d-1)46例,于服药前及服药6个月后测定血压(BP)、左心室舒张末期室间隔厚度(ⅣST)、左心室后壁厚度(LVPWT)、左心室舒张末期直径(LVDd)、左心室重量指数(LVMI)、左心室射血分数(LVEF)、心输出量(CO)和A/E峰值。结果两组治疗后BP、IVST、LVPWT、LVDd、LVMI及A/E峰值均显著降低(P<0.01),其中B组各指标降低更明显,与A组比较有显著差异(P<0.05)。结论依拉普利、厄贝沙坦均能逆转LVH,改善左心室舒张功能,二者合用有明显的协同作用。

关 键 词:原发性高血压  左心室肥厚  依拉普利  厄贝沙坦

Effects of Enalapril and Lrbesartan on Essential Hypertension patients with left cardiac ventricle hypertrophy
Xiemeng,Wang yangfang,XiuMin,et al.. Effects of Enalapril and Lrbesartan on Essential Hypertension patients with left cardiac ventricle hypertrophy[J]. Guizhou Medical Journal, 2004, 28(7): 593-595
Authors:Xiemeng  Wang yangfang  XiuMin  et al.
Affiliation:Xiemeng,Wang yangfang,XiuMin,et al. Zunyi city people's Hospital,563002
Abstract:To evaluate the effects of the retroversion of enalapril and Lrbesartan on essential hypertrophy (LCVH) . Methods 92 cases of EH with LCVH were divided by average into two groups that group A ( Lrbesartan 150mg/d treatment) and group B ( Enalapril 5-10mg/d add Lrbesartan 75mg/d treatment ). Bp, IVST, LBPWT, LVDA, LVMI, LVEF, Co and A/E were measured before and after of treatment 6 months. Results Above targets were decreased more than before in two groups(P<0. 01). Conclusion The Enalapril and Lrbesartan can be improved the function of left cardiac ventrecle.
Keywords:EH LCVH Enalapric Lrbesartan
本文献已被 CNKI 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号