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干休所老干部近10年服用他汀类药物的血脂水平分析
引用本文:徐晓晖,沈琰,刘斌,缪茜,王兵,陈雯. 干休所老干部近10年服用他汀类药物的血脂水平分析[J]. 东南国防医药, 2014, 0(6): 619-620
作者姓名:徐晓晖  沈琰  刘斌  缪茜  王兵  陈雯
作者单位:海军东体育会路离职干部休养所, 上海,200437
摘    要:
目的:调查并分析干休所内60名80岁以上男性老干部服用他汀类药物近10年来血脂变化情况,为进一步做好老干部保健工作提供参考依据。方法收集2005年3月-2014年3月规律服用他汀类药物的男性老干部每年体检的血脂数据,选择60名符合条件者进行回顾性分析,同时观察辛伐他汀和阿托伐他汀的降低血脂作用。结果60名受检者三酰甘油(TG)下降30.4%(P<0.01),总胆固醇(TC)下降39.5%(P<0.01)。低密度脂蛋白(LDL-C)下降26.6%(P<0.01),高密度脂蛋白(HDL-C)升高了11.4%(P<0.05)。自2012年改服阿托伐他汀后,TG、TC和LDL-C水平分别在原有基础上下降19.4%(P<0.01)、21.8%(P<0.01)和17.2%(P<0.01),HDL-C升高8.9%(P<0.05)。结论近10年来规律服用他汀药物的男性老干部血脂水平改善,TG、TC和LDL-C呈下降趋势,HDL-C呈上升趋势,阿托伐他汀较辛伐他汀的降脂效果明显。

关 键 词:血脂  他汀类药物  回顾性分析

Analysize of lipid-lowering therapy with statins in military retirement center in recent ten years
XU Xiao-hui,SHEN Yan,LIU Bin,MIAO Qian,WANG Bing,CHEN Wen. Analysize of lipid-lowering therapy with statins in military retirement center in recent ten years[J]. Journal of Southeast China National Defence Medical Science, 2014, 0(6): 619-620
Authors:XU Xiao-hui  SHEN Yan  LIU Bin  MIAO Qian  WANG Bing  CHEN Wen
Affiliation:( Outpatient Department, Dongtiyuhui Road Military Retire- ment Center, Navy, Shanghai,200437, China)
Abstract:
Objective To investigate the blood lipid level change in the aged above 80 at military retirement center in recent ten years and to improve the future health care work .Methods The health examination data of blood lipid of 60 cases of elderly men age above 80 between March 2005 to March 2014 were collected for retrospective study .Results In past 10 years,the 60 veteran ca-dres'TG and TC decreased 30.4%(P〈0.01) and 39.5%(P〈0.01) separately,LDL-C decreased 26.6%(P〈0.01) and HDL-C increased 11.4%(P〈0.05) in past 9 years.Their TG,TC and LDL-C further decreased 19.4% (P〈0.01),21.8% (P〈0.01) and 17.2%(P〈0.01),HDL-C increased 8.9%(P〈0.05) on the original basis after using the atorvastatin .Conclusion The vet-eran cadres'blood lipid level showed the downtrend but unstable ,compared with simvastatin,atorvastatin had obvious effect on lipid-lowering therapy .
Keywords:blood lipid  statins  retrospective study
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