| 裸鼠体内人类肿瘤杀伤细胞对自体恶性肿瘤杀伤作用的研究 |
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| 引用本文： | 张滨学,唐尧,郑杰,王洁良,由江峰,方伟岗,殷澄,吴秉铨,王秀云,高荣莲. 裸鼠体内人类肿瘤杀伤细胞对自体恶性肿瘤杀伤作用的研究[J]. 北京大学学报(医学版), 1991, 0(6) |
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| 作者姓名： | 张滨学 唐尧 郑杰 王洁良 由江峰 方伟岗 殷澄 吴秉铨 王秀云 高荣莲 |
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| 作者单位： | 北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学病理学教研室，北京医科大学第三医院妇产科，北京医科大学第三医院妇产科 |
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| 摘 要： | 本文利用卵巢癌手术标本建立体外细胞系及裸鼠移植瘤(OEC)。将来自同一病人的脾淋巴细胞体外经重组人类白细胞介素2活化为LAK细胞。裸鼠体内进行的Winn氏中和试验结果表明,L-AK细胞能有效地抑制自体恶性肿瘤在裸鼠体内的成瘤现象。
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| 关 键 词： | 淋巴因子活化杀伤细胞 白细胞介素2 裸鼠 |
RESEARCHES ON THE ANTI-AUTOLOGOUS TUMOR EFFECTS OF HUMAN CANCER-KILLING CELLS IN NUDE MICE |
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| Zhang Binxue,et al. RESEARCHES ON THE ANTI-AUTOLOGOUS TUMOR EFFECTS OF HUMAN CANCER-KILLING CELLS IN NUDE MICE[J]. Journal of Peking University. Health sciences, 1991, 0(6) |
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| Authors: | Zhang Binxue et al |
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| Affiliation: | Zhang Binxue,et al Department of Pathology |
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| Abstract: | Human Ovary Embryo Carcinoma (OEC) removed surgically have been transplanted into nude mi-ce and cultured in vitro, that would be used as targets. Lymphokine-activated killer cells were gener-ated from splenic lymphocytes of the OEC patient through co culturc with recombinant human inter-luekin-2 in vitro. The results of winn's test in nude mice have suggested that the LAK cells couldeffectively inhibit the growth of autologous tumors in vivo. |
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| Keywords: | Lymphokine-activated killer cells Interluekin-2 Nude mice |
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