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蒽环类抗肿瘤抗生素脂质体制剂的研究现状与进展述评
引用本文:陆振举,尹婕,邓盏齐.蒽环类抗肿瘤抗生素脂质体制剂的研究现状与进展述评[J].国外医药(抗生素分册),2009,30(3):106-112.
作者姓名:陆振举  尹婕  邓盏齐
作者单位:中国医药集团,四川抗菌素工业研究所,成都,610052
摘    要:脂质体作为一种微粒类靶向制剂载体具有许多优良的特性,近年来在肿瘤化学治疗中的应用日益广泛。主要介绍几种具有代表性的蒽环类抗肿瘤抗生素多柔比星、表柔比星、柔红霉素、伊达比星、吡柔比星及米托蒽醌的脂质体制剂的上市或研发情况。

关 键 词:蒽环类  抗生素  肿瘤化学治疗  脂质体制剂  药物载体

Research Progress of Lipsomes Application in Anthracycline Antitumor Antibiotic Fomulations
LU Zhen-ju,YING Jie,DENG Sheng-qi.Research Progress of Lipsomes Application in Anthracycline Antitumor Antibiotic Fomulations[J].world notes on antibiotics,2009,30(3):106-112.
Authors:LU Zhen-ju  YING Jie  DENG Sheng-qi
Institution:LU Zhen-ju,YING Jie,DENG Sheng-qi (Department of Pharmaceutical Chemistry,Sichuan Industrial Institute of Antibiotics,China National Pharmaceutical Group Corporation,Chengdu 610052,China)
Abstract:Lipsomes, as a particulate-type targeted drug carrier, possess many excellent characteristics. They have been increasely used in cancer chemotherapy in recent years. This article introduces the research progress and marketing status of several important lipsomes of anthracycline antitumor antibiotics, such as doxorubicin, epirubicin, daunorubicin, idrubocin, piraubicin and mitoxantrone.
Keywords:anthracycline  antibiotics  cancer chemotherapy  lipsomes  drug carrier  
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