|
|||||
|
|
| 用正交函数分光光度法测定多相脂质体中的氟尿嘧啶 | |
| 引用本文： | 张玉琴,刘世庆,徐莉英,顾学裘. 用正交函数分光光度法测定多相脂质体中的氟尿嘧啶[J]. 沈阳药科大学学报, 1987, 0(3) |
| 作者姓名： | 张玉琴 刘世庆 徐莉英 顾学裘 |
| 作者单位： | 沈阳药学院分析化学教研室(张玉琴，刘世庆，徐莉英)，沈阳药学院制剂研究室(顾学裘) |
| 摘 要： | 用正交函数分光光度法可以同时消除尼泊金和基质的干扰,简单、快速地测定抗癌药物新剂型—多相脂质体口服三号中氟尿嘧啶的含量。经实验表明,选择二次正交多项式(j=2),波长点数N=7,波长间隔△λ=1nm,中间波长λm=265.5nm时,测定准确度最高,适用于一般常规分析。 |
| 关 键 词： | 正交函数分光光度法 氟尿嘧啶 多相脂质体 |
SPECTROPHOTOMETRIC DETERMINATION OF FLUOROURACILUM IN POLYPHASE LIPOSOME USING ORTHOGONAL POLYNOMIALS |
|
| Zhang Yuqin Liu Shiqing Xu Liying. SPECTROPHOTOMETRIC DETERMINATION OF FLUOROURACILUM IN POLYPHASE LIPOSOME USING ORTHOGONAL POLYNOMIALS[J]. Journal of Shenyang Pharmaceutical University, 1987, 0(3) | |
| Authors: | Zhang Yuqin Liu Shiqing Xu Liying |
| Affiliation: | Zhang Yuqin Liu Shiqing Xu Liying Department of Analytical Chemistry Gu Xueqiu Ressearch Department of pharmacy |
| Abstract: | This paper reports a spectrophotometric determination method of fluorouracilum in polyphase liposome using orthogonal polynomials. In this method the samples need no separating,and fluorouracilum content can be directly determined.The method is simple,rapid and accurate.Experiments have indicated that the second order orthogonal polynomials are desirable. The coefficient b_2 is calculated with wavelength intervals at lnm and medial wavelength at 265.5nm. |
| Keywords: | Spectrophotometry of orthogonal polynomials Fluorouracilum Polyphase liposome |
| 本文献已被 CNKI 等数据库收录！ | |