MRI在视神经脊髓炎诊断及随访观察中的应用价值

目的:探讨MRI在视神经脊髓炎诊断及随访观察中的应用价值。方法:回顾性分析14例视神经脊髓炎的临床与MRI表现及影像学系列变化的特点。结果:视神经脊髓炎可相继累及视神经和脊髓,也可同时累及视神经与脊髓,发病初期MRI表现为视神经和脊髓的增粗,T2WI像呈条片状高信号,T1WI上呈等低信号,Gd-DTPA增强可呈不规则强化,治疗后异常信号及异常强化可消失,随访观察病变可反复出现,并可导致视神经和脊髓萎缩变细。结论:MRI能够提供视神经脊髓炎诊断的影像学改变的直接依据,在本病的诊断、鉴别诊断及病变的随访观察中有重要的临床应用价值。

The application value of MRI in the diagnosis and follow-up survey of neuromyelitis optica

Objective:To investigate the application value of MRI in the diagnosis and follow-up survey of neuromyelitis optica.Methods:The clinical and MRI findings,series imaging changes of 14 cases neuromyelitis optica were retrospective analyzed.Results:The optic nerve and spinal cord were invaded in succession or at the same time by the neuromyelitis optica.The optic nerve and spinal cord became thickness in the incipience of neuromyelitis optica,the high signals in T_2WI and the equal or low signals in T_1WI.The foci enhanced irregular when injected Gd-DTPA contrast media through vein.The abnormal signals and enhancement disappeared after the treatment,and that can be appeared repetitively,then the atrophy of optic nerve and spinal cord were often seen in the follow-up survey.Conclusion:MRI can provide the direct imaging evidence for the diagnosis of neuromyelitis optica and it was important in the diagnosis,differential diagnosis and follow-up survey of neuromyelitis optica.