| 琥珀酸羟基哌喹治疗实验性肝损害的初步观察 |
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| 引用本文： | 王国俊,瞿瑶,杨宗岳,王爱华,许德余,宋仁德,冯宝鑫,楼方岑.琥珀酸羟基哌喹治疗实验性肝损害的初步观察[J].第二军医大学学报,1985(6). |
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| 作者姓名： | 王国俊 瞿瑶 杨宗岳 王爱华 许德余 宋仁德 冯宝鑫 楼方岑 |
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| 作者单位： | 第二军医大学第二附属医院传染科
(王国俊，瞿瑶，宋仁德)，第二军医大学第二附属医院实验科
(杨宗岳，王爱华)，第二军医大学抗疟药研究室
(许德余)，上海市传染病院病理室
(冯宝鑫)，第二军医大学第二附属医院传染科(楼方岑) |
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| 摘 要： | 本文报告了用D-氨基半乳糖诱发急性肝炎动物模型,以琥珀酸羟基哌喹治疗30天,通过ALT、AST及淋巴细胞转化率测定和肝脏病理观察结果表明,琥珀酸羟基哌喹能增强细胞免疫功能,减轻肝脏病变程度和捉进实验性肝炎的恢复。
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| 关 键 词： | 肝炎 急性 琥珀酸羟基哌喹 疾病模型 动物 大鼠 |
PRELIMINARY OBSERVATION ON THE TREATMENT OF THE EXPERIMENTAL HEPA TIC INJURIES |
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| Wang Guojun,et al..PRELIMINARY OBSERVATION ON THE TREATMENT OF THE EXPERIMENTAL HEPA TIC INJURIES[J].Academic Journal of Second Military Medical University,1985(6). |
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| Authors: | Wang Guojun |
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| Abstract: | An experiment of treatment with hydroxypiperaquine succinate on the acute hepatic injuries induced by D-galactosamine were observed. The level of ALT, AST and lymphoblastic transformation were evaluated, and the liver specimens were investigated microscopically. The results showed that the hydroxypiperaquine succinate can enhance the cellular immunization, and can lighten the pathological changes of liver and promote the recovery from hepatitis. |
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| Keywords: | therapy experiments hydroxypiperaquine disease models animal rats |
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