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西酞普兰与米氮平治疗老年期抑郁症对照研究
引用本文:魏冬,刘蕴霞,席永稳. 西酞普兰与米氮平治疗老年期抑郁症对照研究[J]. 中国民康医学, 2009, 21(14): 1651-1651,1759. DOI: 10.3969/j.issn.1672-0369.2009.14.028
作者姓名:魏冬  刘蕴霞  席永稳
作者单位:河南省洛阳市第五人民医院老年科,河南,洛阳,471000
摘    要:
目的:比较西酞普兰与米氮平治疗老年期抑郁症的疗效和不良反应.方法:将64例老年期抑郁症患者随机分成两组,疗程8周,采用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)评定疗效和不良反应.结果:西酞普兰组和米氮平组显效率分别82.35%和76.7%,两组疗效差异无显著性(P>0.05),西酞普兰的不良反应少于米氮平.结论:西酞普兰是一种安全、有效的抗抑郁药.

关 键 词:西酞普兰  米氮平  老年期抑郁症

Citalopram with Mirtazapine treatment senile depression
WEI Dong,LIU Yun-xia,XI Yong-weng. Citalopram with Mirtazapine treatment senile depression[J]. medical journal of chinese peoples health, 2009, 21(14): 1651-1651,1759. DOI: 10.3969/j.issn.1672-0369.2009.14.028
Authors:WEI Dong  LIU Yun-xia  XI Yong-weng
Abstract:
Objective:To explore the efficacy and side effects of citalopram and mirtazapine in treatment of senile depression.Methods:64 senile depressive patients were randomly divided into two groups for 8 weeks.The trerapeutic response and side effects were evaluated with the HAMD and TESS.Results:The effective rates of citalopram and mirtazapine were 82.35% and 76.7% respectively there were no significant difference in efficacy between the two groups (P>0.05),citalopram had fewer side effects than mirtazapine.Conclusion:Citalopram is a safe and effective antidepressant.
Keywords:Citalopram  Mirtazapine  Senile depression
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