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Morphological study of the effects of textile-immobilized enzymes on an experimental purulent wound
Authors:P. I. Tolstykh  T. E. Ignatyuk  V. K. Gostishehev
Affiliation:(1) State Scientific Center for Laser Medicine, Moscow
Abstract:
Morphological changes in an experimental purulent wound in a rat model is studied for application of surgical gauze with immobilized enzymes: trypsin, lysozyme, collitin, or co-immobilized trypsin and lysozyme. Comparison of the times of wound cleansing and healing shows that immobilized enzymes are more effective than native preparations, and the therapeutic effect of gauze with the enzyme complex is higher than that of gauze with individually immobilized enzymes. Morphological studies confirm that immobilized trypsin-lysozyme complex and collitin are the most efficient in hastening and potentiating reparative procevesses in a purulent wound. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N o , 9, pp. 323–325, September, 1994
Keywords:purulent wound    healing    immobilized enzymes
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