早期气管插管机械通气对抢救有机磷中毒呼吸衰竭的治疗意义

目的 探讨早期气管插管机械通气对抢救有机磷中毒所致呼吸衰竭的治疗意义.方法 对64例急性有机磷中毒致呼吸衰竭患者行气管插管机械通气治疗,根据呼吸指标及动脉血气分析指标分为常规插管组30例和早期插管组34例,比较两组插管前后动脉血气分析和心率（HR）的变化及治疗效果.结果 气管插管前常规插管组动脉血氧分压（PaO2）、血氧饱和度（SaO2）较早期插管组明显降低（P〈0.05）;两组插管前后PaO2、二氧化碳分压（PaCO2）、SaO2及HR比较差异均有统计学意义（P〈0.05）;早期插管组治愈率明显高于常规插管组（P〈0.01）.结论 急救早期气管插管机械通气治疗能明显提高有机磷中毒所致呼吸衰竭患者的抢救成功率.

Significance of emergency early trachea cannula and mechanical ventilation in the treatment of respiratory failure due to organophosphate poisoning

Objective To explore the significance of emergency early trachea cannula and mechanical ventilation in the treatment of respiratory failure due to organophosphate poisoning. Methods Sixty-four patients with the respiratory failure due to acute ganophosphate poisoning were divided in two groups according to breathing indicatiors of blood analysis. The conventional intubafion group （30 patients） was treated by conventional method. The early intubation group （34 patients） was treated by trachea cannula and mechanical ventilation. The results of blood analysis, changes of heart rate ,therapeutic effect before and after treatment between two groups were compared. Results The arterial oxygen tension （PaO2 ）, oxygen saturation （SaO2 ） in the conventional intubation group was significantly lower than those in the early intubation group （P 〈 0. 05 ）. There were statistically significant difference in PaO2, partial pressure of carbon dioxide （ PaCO2 ）, SaO2 and HR differences before and after treatment between two groups （P 〈 0. 05 ）. The cure rate in early intubation group was significantly higher than that in the conventional intubation group （P 〈 0. 01 ）. Conclusion Emergency early trachea cannula machanical ventilation can obviously raise the rescure success rate of respiratory failure due to ganophosphate poisoning.