肺炎性肌纤维母细胞瘤的临床及病理特征

目的:探讨肺炎性肌纤维母细胞瘤的临床及病理特点。方法:回顾分析3例肺炎性肌纤维母细胞瘤的临床资料。3例患者均有不同程度的咳嗽及咳痰,其中1例出现痰中带血,经胸部影像学诊断为左上肺占位2例,右上肺占位1例;3例患者均行肺叶切除。结果:3例患者均经手术完整切除肿块,均无围手术期并发症,术后经病理及免疫组化检查均符合肺炎性肌纤维母细胞瘤,患者平滑肌肌动蛋白(smooth muscle actin,SMA)均为部分阳性。结论:手术切除是治疗肺炎性肌纤维母细胞的有效手段,因部分病例会出现复发及转移,故有必要进行长期随访。

Clinicopathological Features of Inflammatory Myofibroblastic Tumor of the Lung

Objective： To study the clinical, pathological and immunohistochemical features of inflammatory myofibroblastic tumor （IMT） of the lung. Methods：Three patients with IMT of the lung have been enrolled. Chest radiograph and computed tomography of the chest revealed two masses in the left upper lobe and one mass in the right upper lobe. All the 3 cases under- went pulmonary lobectomy and local lymph nodes dissection. Results： All masses have been resected successfully. No intraop erative or perioperative complications occurred. Smooth muscle actin （SMA） were positive in all cases. Conclusions： Complete surgical resection of inflammatory myofibroblastie tumor of the lung is usually curative, but local recurrence may occur years af ter the surgery, therefore clinical follow-up is necessary.