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The effects of strength,aerobic, and concurrent exercise on skeletal muscle damage in rats
Authors:Anderson Rech MS  Regis Radaelli MS  Adriano M. De Assis PhD  João R. Fernandes MS  Aline Longoni PhD  Magdolna M. Vozari‐Hampe PhD  Ronei S. Pinto PhD  Cristiane Matté PhD
Affiliation:1. Exercise Research Laboratory, School of Physical Education, Federal University of Rio Grande do Sul, , Porto Alegre, RS, 90690‐200 Brazil;2. Department of Biochemistry, Federal University of Rio Grande do Sul, , Porto Alegre, RS, Brazil
Abstract:
Introduction: In this study we examined oxidative stress and skeletal muscle damage resulting from acute strength, aerobic, or concurrent exercise in rats. Methods: The animals were divided into control (C), strength (SE), aerobic (AE), and combined (CE) exercise groups. They were euthanized at 3 different time‐points (6, 24, and 48 h) after acute exercise. Results: SE exercise rats had increased dichlorofluorescein oxidation at 6 h post‐exercise and decreased superoxide dismutase activity at all time‐points. Glutathione peroxidase activity and sulfhydryl levels were increased in the AE group at 48 h post‐exercise. Serum lactate dehydrogenase activity was increased in the SE and CE groups at 24 h and in the AE group at 48 h. Echo intensity was elevated at 24 h for all groups. Conclusions: Forty‐eight hours was sufficient for complete recovery from oxidative stress and muscle damage in the SE and CE groups, but not in the AE group. Muscle Nerve 50 : 79–86, 2014
Keywords:concurrent exercise  exercise recovery  gastrocnemius  muscle damage  oxidative stress
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