华蟾素注射液和艾迪注射液治疗晚期肺癌的对比研究

目的探讨华蟾素注射液和艾迪注射液对晚期肺癌的干预作用。方法将60例晚期肺癌患者随机分为2组,华蟾素组30例,采用华蟾素注射液加基础治疗;艾迪组30例,采用艾迪注射液加基础治疗。分别观察临床综合疗效、症候总积分、主要症状积分、Karnofsky评分,以及肿瘤标志物(CEA、CA125)的变化。1个月为1个疗程,共观察3个疗程。结果治疗后,在临床综合疗效和症候总积分改善方面,2组比较,差异无显著性;在肺癌气阴两虚证主要症状积分、Karnofsky评分,以及肿瘤标志物水平改善方面,艾迪组优于华蟾素组(P<0.05)。结论针对晚期肺癌气阴两虚证患者,华蟾素注射液和艾迪注射液均有较好的疗效,但是,由于艾迪注射液是多成分的中药复方制剂,更加适合于晚期肺癌气阴两虚证患者。

Comparative Study Of Advanced Lung Cancer with Huachansu Injection And Aidi Injection

Objective To study the effect of huachansu injection(HCS) and aidi injection(AD) on advanced lung cancer.Methods Sixty patients were randomly assigned into 2 groups: the HCS group(30 cases) was treated with HCS injection and basal therapy;the AD group(30 cases) was treated with AD injection and basal therapy.Changes of clinical total effective rate,total score of syndromes,score of main symptoms,Karnofsky score as well as the serum levels of tumor markers(CEA,CA125) were observed.With one month as a course of treatment,three courses were observed.Results After treatment,the clinical total effective rate and improvement in the total score of syndromes showed insignificant difference between 2 groups;but in the score of main symptoms,Karnofsky score and the serum levels of tumor markers,AD group was better than HCS group(P<0.05).Conclusion Both HCS injection and AD injection have good effects in treating advanced lung cancer with Qi-Yin asthenia syndrome(QYAS).AD injection is more effective for lung cancer in the advanced stage with QYAS than HCS injection because the former is a compound preparation of multiple Chinese herbal-medicine ingredients.