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左旋 氟沙星治疗单纯性淋病合并衣原体和/或支原体感染的临床观察
引用本文:赖维,张玉清,朱国兴,黄怀球,陈荣章.左旋 氟沙星治疗单纯性淋病合并衣原体和/或支原体感染的临床观察[J].中国皮肤性病学杂志,2001,15(1):32-34.
作者姓名:赖维  张玉清  朱国兴  黄怀球  陈荣章
作者单位:中山医科大学附属第三医院皮肤性病科,
摘    要:目的比较两种治疗方案(左旋氧氟沙星200mg2次/d共7天与头孢三嗪250mg单剂量肌注加强力霉素100mg2次/d共7天)治疗单纯性淋病合并衣原体和/或支原体感染各30例的有效性和安全性。方法采用随机、开放、对照研究,试验组及对照组各30例。结果两组病例的痊愈率分别为83.33%和86.67%,总有效率为90%和93.33%,差异无显著性(P>0.05);副反应发生率分别为3.33%和16.67%,差异有显著性(P<0.05)。结论口服左旋氧氟沙星方案可作为治疗淋病合并衣原体和/或支原体感染的治疗方法之一。

关 键 词:淋病  尿道炎,非淋菌性  左旋氧氟沙星  头孢三嗪  强力霉素
文章编号:1001-7089(2001)01-0032-03
修稿时间:1999年12月22

Clinical Comparing Study of the Tfficacy of the Treatment of Uncomplicated Gonorrhea Co-infected Chlamydia trachomatis and Mycoplasma by Levofloxacin or Cetriaxone Pulse Doxycycline
Abstract:Objective To compare the efficacy and safety of two regimens in the treatment of uncomplicated gonorrhae co infected with chlamydia/mycoplsma. Methods A randomized, open, and parallel control clinical trial. Group A was treated with Levofloxacin 200mg, two times daily for 7 days;Group B was treated with Ceftriaxone 250mg, intramascularly for single dose plus Doxycline 100mg, two times daily for 7days. Results Each group had 30 patients, the efficacy rate for group A and group B was 90% and 93.3% respectively, no significant difference was found between two groups( P>0.05);the occurring rate of adverse effects was 3.33% and 16.67% respectively, a significant difference existed between the two groups( P<0.05). Conclusion Levofloxacin can be used in treatment for uncomplicated gonorrhae co-infected with chlamydia/mycoplsma effectively and safety.
Keywords:Gonorrhea  Nongorcoccal Urethritis  Levofloxacin  Cetriaxone  Doxycycline
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