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| 间充质干细胞应用于器官移植的研究进展 | |
| 引用本文： | 林金芳,吴卫真. 间充质干细胞应用于器官移植的研究进展[J]. 国际外科学杂志, 2014, 0(5): 342-344 |
| 作者姓名： | 林金芳 吴卫真 |
| 作者单位： | 南京军区福州总医院泌尿外科,福州350025 |
| 摘 要： | 器官移植是治疗终末期器官衰竭的唯一选择,但术后排斥反应制约了其疗效.间充质干细胞所表现出一些理想的特性,包括：移植同种异体反应和自身免疫性T细胞应答,促进细胞因子环境,这些特性可能对移植物有保护作用,故主张在器官移植中应用.本文对近年来间充质干细胞应用于器官移植的研究进展作一综述. |
| 关 键 词： | 间充质干细胞 肾移植 急性排斥反应 综述 |
Research of mesenchymal stem cells used in organ transplantation |
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| Lin Jinfang,Wu Weizhen. Research of mesenchymal stem cells used in organ transplantation[J]. International Journal of Surgery, 2014, 0(5): 342-344 | |
| Authors: | Lin Jinfang Wu Weizhen |
| Affiliation: | ( Institute of Organ Transplantation, Fuzhou General Hospital, Fuzhou 350025, China) |
| Abstract: | Transplantation is regarded as the only therapeutic choice for end-stage organ failure,however,rejection restricted its efficacy after transplantation.MSCs exhibit several desirable characteristics,which may advocate their use in organ transplantation.This includes the capacity to suppress alloreactive and autoimmune T-cell responses,and pro mote a cytokine environment which is likely to be graft protective.This review describes the recent research of MSCs used in organ transplant. |
| Keywords: | Mesenchymal stem cells Kidney transplantation Acute rejection Review |
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