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Tick-Borne Encephalitis Virus (TBEV) Infection in Two Horses
Authors:Theresa Maria Conze,Zoltá  n Bagó  ,Sandra Revilla-Ferná  ndez,Jü  rgen Schlegel,Lutz S. Goehring,Kaspar Matiasek
Abstract:
A final diagnosis in a horse with clinical signs of encephalopathy can be challenging despite the use of extensive diagnostics. Clinical signs are often not pathognomonic and need to be interpreted in combination with (specific) laboratory results and epidemiological data of the geographical region of the origin of the case(s). Here we describe the diagnostic pathway of tick-borne encephalitis virus infection in two horses using established molecular diagnostic methods and a novel in situ hybridization technique to differentiate between regionally important/emerging diseases for central Europe: (i) hepatoencephalopathy, (ii) Borna disease virus, and (iii) West Nile virus infections.
Keywords:encephalopathy   Borna disease virus (BoDV)   West Nile virus (WNV)   in situ hybridization   clinical case
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