Effect of the COVID-19 pandemic on ST-elevation myocardial infarction presentation and survival |
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| Authors: | Sachintha Perera Sudhir Rathore Joanne Shannon Peter Clarkson Matthew Faircloth Vinod Achan |
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| Affiliation: | Internal Medicine Trainee Frimley STEMI Research Group, Department of Cardiology, Frimley Park Hospital, Portsmouth Road, Frimley, Camberley, Surrey, GU16 7UJ;Consultant Cardiologist Frimley STEMI Research Group, Department of Cardiology, Frimley Park Hospital, Portsmouth Road, Frimley, Camberley, Surrey, GU16 7UJ |
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| Abstract: | Presentation and outcomes of patients with ST-elevation myocardial infarction (STEMI) may change during viral pandemics. We compared symptom-tocall (STC), call-to-balloon (CTB), doorto-balloon (DTB) times; high-sensitivity troponin (hs-cTnI) levels; and survival of patients (n=39) during the first wave of the COVID-19 pandemic (defined as a ‘COVID period’ starting four weeks before lockdown) to historical controls from a ‘pre-COVID period’ (n=45).STEMI admissions fell one week before lockdown by 29%. Median STC times began to rise one month before lockdown (54 vs. 25 min, p=0.06), with peak increases between 9 March and 5 April (166 vs. 59 min, p=0.04). Median CTB and DTB times were unchanged. Mean peak hs-cTnI increased during COVID-19 (15,225 vs. 8,852 ng/ml, p=0.004). Six-month survival following all STEMI reduced (82.1% vs. 95.6%, p<0.05).STC times are the earliest indicator that STEMI-patient behaviour changed four weeks before lockdown, correlating with higher troponin levels and reduced survival. These early signals could guide public health interventions during future pandemics.Key words: COVID-19, outcomes, percutaneous coronary intervention (PCI), ST-elevation myocardial infarction (STEMI) |
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