母孕期维生素D水平与婴儿体格生长的相关性研究

目的 探讨母孕期维生素D水平与婴儿体格生长的相关性。方法 检测孕晚期孕妇血清和新生儿脐血的25-(OH)D;并测量出生时、3、6、8月龄婴儿的体格生长指标及3、6、8月龄胫骨超声骨强度。结果 223例孕母血清25-(OH)D水平为(50.7±18.5)nmol/L,与婴儿体格生长指标无相关性;孕母与新生儿25-(OH)D水平呈正相关,并存在季节差异。结论 孕期维生素D水平与婴儿体格生长无相关性。

Maternal vitamin D status and the effect on physical growth of infants

Objective To investigate the maternal vitamin D status and the effect of maternal vitamin D during pregnancy on physical growth of infants. Methods 25-(OH)D concentrations were measured in late pregnancy and neonatal umbilical venous serum.Anthropometry of infant was recorded at birth,3,6,and 9 months.Tibial quantitative ultrasonometry was done at 3,6,and 9 months.Atopic eczema was assessed. Results The level of 223 cases of maternal serum 25-(OH)D was (50.7±18.5)nmol/L.There were no associations between maternal 25-(OH)D concentrations and physical growth of infants.There was a positive correlation between maternal and neonatal 25-(OH)D.Both maternal and neonatal 25-(OH)D levels varied with season. Conclusion There are no associations between maternal vitamin D status and physical growth of infant.