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Dr operon-associated invasiveness of Escherichia coli from pregnant patients with pyelonephritis
Authors:Goluszko P  Niesel D  Nowicki B  Selvarangan R  Nowicki S  Hart A  Pawelczyk E  Das M  Urvil P  Hasan R
Affiliation:Departments of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA. pgoluszk@utmb.edu
Abstract:We used a gentamicin protection assay to assess the ability of gestational pyelonephritis isolates of Escherichia coli to invade HeLa cells. The ability to enter HeLa cells was strongly associated with the presence of Dr operons coding for Dr adhesins. In contrast, the nonivasive isolates predominantly expressed papG, coding for P fimbriae.
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