A fatal case of fulminant myocarditis with human herpesvirus-6 infection |
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Authors: | Fukae S Ashizawa N Morikawa S Yano K |
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Institution: | Third Department of Internal Medicine, Nagasaki University School of Medicine. |
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Abstract: | We report a case of fulminant myocarditis after steroid pulse therapy for acute hepatitis. Serological studies demonstrated a four-fold increase in the antibodies against human herpesvirus-6 (HHV-6) IgG, and a PCR showed the existence of HHV-6 virus DNA. HHV-6 virus DNA was also isolated from the liver and the heart. We believe that exacerbation of fulminant myocarditis was probably associated with the reactivation of HHV-6 due to the immunosuppressive state of the host. |
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